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2006 Workshop on Learning & Memory:
Information Flow into Hippocampal Memory Stores

August 3, 2006
9:00 AM - 5:30 PM
Candle House Loft Conference Room

Two independent streams of information flow in parallel to the dentate gyrus of the hippocampus forming the lateral and medial inputs. These streams become combined in the dentate gyrus of the hippocampus, leading to a unique coding of memory information. We will discuss the possible basis of the dual input (see possibilities above) and how this information is combined with feedback information carried by mossy cells.

Schedule:

9:00-9:15 John E. Lisman, Brandeis University - Overview of issues

9:15-9:45 Rebecca D. Burwell, Brown University - Dual cortical systems bring information to the dentate gyrus (hippocampus), forming the basis of the medial and lateral perforant paths

9:45-10:15 Deepak Pandya, Boston University Medical School - The cortex as a mosaic of regions with different evolutionary origins; implications for memory

10:15-10:30 Discussion

10:45-11:15 Anton M. Sirota (Buzsaki), Rutgers University - How up-states in cortical neurons underlie conditional communication between the entorhinal cortex and hippocampus

11:15-11:45 James J. Knierim, University of Texas Medical School - What recordings in the awake animals reveal about the differences in the medial and lateral perforant path

11:45-12:15 Raymond P. Kesner, University of Utah - What behavioral considerations tell us about the medial and lateral perforant path inputs

12:15-12:30 Discussion

1:45-2:15 Brian E. Derrick, University of Texas - Pharmacological and physiological differences of the medial and lateral perforant path: Rules of synaptic modulation and LTP

2:15-2:30 Discussion

2:30-3:00 Helen E. Scharfman, Helen Hayes Hospital - The third input to the dentate gyrus: Feedback pathways provide flow of information from CA3 back to the dentate

3:00-3:15 John E. Lisman, Brandeis University - CA3/dentate interaction as a mechanism for storage and recall of memory sequences

3:30-5:30 Data blitz – Speakers and audience members are welcome to a 5-minute presentation on relevant material; 2 slides maximum


This workshop is sponsored by the Dart Foundation and organized by John Lisman and Helen Sharfman.

Open to the public.